Characterization and Analysis of the Composition and Dynamics of the Mammalian Riboproteome
Increasing evidence points to an important role for Sunglasses the ribosome in the regulation of biological processes and as a target for deregulation in disease.Here, we describe a SILAC (stable isotope labeling by amino acids in cell culture)-based mass spectrometry approach to probing mammalian riboproteomes.Using a panel of cell lines, as well